The Journal of Immunology: 190 (8)

April 15, 2013; Volume 190,Issue 8

IN THIS ISSUE

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In This Issue
J Immunol April 15, 2013, 190 (8) 3829-3830; DOI: https://doi.org/10.4049/jimmunol.1390014

BRIEF REVIEWS

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Complement in Immune and Inflammatory Disorders: Pathophysiological Mechanisms
Daniel Ricklin and John D. Lambris

J Immunol April 15, 2013, 190 (8) 3831-3838; DOI: https://doi.org/10.4049/jimmunol.1203487
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Complement in Immune and Inflammatory Disorders: Therapeutic Interventions
Daniel Ricklin and John D. Lambris

J Immunol April 15, 2013, 190 (8) 3839-3847; DOI: https://doi.org/10.4049/jimmunol.1203200

CUTTING EDGE

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Cutting Edge: Cell Surface Linker for Activation of T Cells Is Recruited to Microclusters and Is Active in Signaling
Lakshmi Balagopalan, Valarie A. Barr, Robert L. Kortum, Anna K. Park and Lawrence E. Samelson

J Immunol April 15, 2013, 190 (8) 3849-3853; DOI: https://doi.org/10.4049/jimmunol.1202760
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Cutting Edge: Rapid Boosting of Cross-Reactive Memory CD8 T Cells Broadens the Protective Capacity of the Flumist Vaccine
Bram Slütter, Lecia L. Pewe, Peter Lauer and John T. Harty

J Immunol April 15, 2013, 190 (8) 3854-3858; DOI: https://doi.org/10.4049/jimmunol.1202790

ALLERGY AND OTHER HYPERSENSITIVITIES

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Dose-Dependent Effects of IL-17 on IL-13–Induced Airway Inflammatory Responses and Airway Hyperresponsiveness
Margaret W. Kinyanjui, Jichuan Shan, Emily M. Nakada, Salman T. Qureshi and Elizabeth D. Fixman

J Immunol April 15, 2013, 190 (8) 3859-3868; DOI: https://doi.org/10.4049/jimmunol.1200506

ANTIGEN RECOGNITION AND RESPONSES

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Discovery of T Cell Epitopes Implementing HLA-Peptidomics into a Reverse Immunology Approach
Pleun Hombrink, Chopie Hassan, Michel G. D. Kester, Arnoud H. de Ru, Cornelis A. M. van Bergen, Harm Nijveen, Jan W. Drijfhout, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk and Peter A. van Veelen

J Immunol April 15, 2013, 190 (8) 3869-3877; DOI: https://doi.org/10.4049/jimmunol.1202351
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Multiple Transcription Factor Binding Sites Predict AID Targeting in Non-Ig Genes
Jamie L. Duke, Man Liu, Gur Yaari, Ashraf M. Khalil, Mary M. Tomayko, Mark J. Shlomchik, David G. Schatz and Steven H. Kleinstein

J Immunol April 15, 2013, 190 (8) 3878-3888; DOI: https://doi.org/10.4049/jimmunol.1202547

AUTOIMMUNITY

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Exacerbated Autoimmunity in the Absence of TLR9 in MRL.Fas^lpr Mice Depends on Ifnar1
Kevin M. Nickerson, Jaime L. Cullen, Michael Kashgarian and Mark J. Shlomchik

J Immunol April 15, 2013, 190 (8) 3889-3894; DOI: https://doi.org/10.4049/jimmunol.1203525
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Divergent Effects of T Cell Costimulation and Inflammatory Cytokine Production on Autoimmune Peripheral Neuropathy Provoked by Aire Deficiency
Xiaopei L. Zeng, Anil Nagavalli, Colin-Jamal Smith, James F. Howard and Maureen A. Su

J Immunol April 15, 2013, 190 (8) 3895-3904; DOI: https://doi.org/10.4049/jimmunol.1203001
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The Downregulation of microRNA let-7a Contributes to the Excessive Expression of Type I Collagen in Systemic and Localized Scleroderma
Katsunari Makino, Masatoshi Jinnin, Ayaka Hirano, Keitaro Yamane, Mitsuhiko Eto, Takamitsu Kusano, Noritoshi Honda, Ikko Kajihara, Takamitsu Makino, Keisuke Sakai, Shinichi Masuguchi, Satoshi Fukushima and Hironobu Ihn

J Immunol April 15, 2013, 190 (8) 3905-3915; DOI: https://doi.org/10.4049/jimmunol.1200822
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Maintenance of Anti-Sm/RNP Autoantibody Production by Plasma Cells Residing in Ectopic Lymphoid Tissue and Bone Marrow Memory B Cells
Jason S. Weinstein, Matthew J. Delano, Yuan Xu, Kindra M. Kelly-Scumpia, Dina C. Nacionales, Yi Li, Pui Y. Lee, Philip O. Scumpia, Lijun Yang, Eric Sobel, Lyle L. Moldawer and Westley H. Reeves

J Immunol April 15, 2013, 190 (8) 3916-3927; DOI: https://doi.org/10.4049/jimmunol.1201880
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Agonistic Anti-CD40 Induces Thyrocyte Proliferation and Promotes Thyroid Autoimmunity by Increasing CD40 Expression on Thyroid Epithelial Cells
Timothy Kayes, Yujiang Fang, Shiguang Yu, Edward Downey, Shufang Wang and Helen Braley-Mullen

J Immunol April 15, 2013, 190 (8) 3928-3938; DOI: https://doi.org/10.4049/jimmunol.1202929

CLINICAL AND HUMAN IMMUNOLOGY

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Conversion of Peripheral Blood NK Cells to a Decidual NK-like Phenotype by a Cocktail of Defined Factors
Ana Sofia Cerdeira, Augustine Rajakumar, Caroline M. Royle, Agnes Lo, Zaheed Husain, Ravi I. Thadhani, Vikas P. Sukhatme, S. Ananth Karumanchi and Hernan D. Kopcow

J Immunol April 15, 2013, 190 (8) 3939-3948; DOI: https://doi.org/10.4049/jimmunol.1202582
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Functional Genetic Variation in NFKBIA and Susceptibility to Childhood Asthma, Bronchiolitis, and Bronchopulmonary Dysplasia
Salman Ali, Aaron F. Hirschfeld, Matthew L. Mayer, Edgardo S. Fortuno, Nathan Corbett, Maia Kaplan, Shirley Wang, Julia Schneiderman, Christopher D. Fjell, Jin Yan, Loubna Akhabir, Farzian Aminuddin, Nico Marr, Thierry Lacaze-Masmonteil, Richard G. Hegele, Allan Becker, Moira Chan-Yeung, Robert E. W. Hancock, Tobias R. Kollmann, Denise Daley, Andrew J. Sandford, Pascal M. Lavoie and Stuart E. Turvey

J Immunol April 15, 2013, 190 (8) 3949-3958; DOI: https://doi.org/10.4049/jimmunol.1201015
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Anti–GM-CSF Autoantibodies in Patients with Cryptococcal Meningitis
Lindsey B. Rosen, Alexandra F. Freeman, Lauren M. Yang, Kamonwan Jutivorakool, Kenneth N. Olivier, Nasikarn Angkasekwinai, Yupin Suputtamongkol, John E. Bennett, Vasilios Pyrgos, Peter R. Williamson, Li Ding, Steven M. Holland and Sarah K. Browne

J Immunol April 15, 2013, 190 (8) 3959-3966; DOI: https://doi.org/10.4049/jimmunol.1202526
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Antigen-Reactive T Cell Enrichment for Direct, High-Resolution Analysis of the Human Naive and Memory Th Cell Repertoire
Petra Bacher, Christian Schink, Janka Teutschbein, Olaf Kniemeyer, Mario Assenmacher, Axel A. Brakhage and Alexander Scheffold

J Immunol April 15, 2013, 190 (8) 3967-3976; DOI: https://doi.org/10.4049/jimmunol.1202221

IMMUNE REGULATION

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IL-21 Promotes CD8⁺ CTL Activity via the Transcription Factor T-bet
Andrew P. R. Sutherland, Nicole Joller, Monia Michaud, Sue M. Liu, Vijay K. Kuchroo and Michael J. Grusby

J Immunol April 15, 2013, 190 (8) 3977-3984; DOI: https://doi.org/10.4049/jimmunol.1201730
Open Access
Clonally Diverse T Cell Homeostasis Is Maintained by a Common Program of Cell-Cycle Control
Author Choice Article

Thea Hogan, Andrey Shuvaev, Daniel Commenges, Andrew Yates, Robin Callard, Rodolphe Thiebaut and Benedict Seddon

J Immunol April 15, 2013, 190 (8) 3985-3993; DOI: https://doi.org/10.4049/jimmunol.1203213
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Ly49Q Positively Regulates Type I IFN Production by Plasmacytoid Dendritic Cells in an Immunoreceptor Tyrosine–Based Inhibitory Motif–Dependent Manner
Mir Munir A. Rahim, Lee-Hwa Tai, Angela D. Troke, Ahmad Bakur Mahmoud, Elias Abou-Samra, Justin G. Roy, Amelia Mottashed, Nicholas Ault, Chloe Corbeil, Marie-Line Goulet, Haggag S. Zein, Melisa Hamilton-Valensky, Gerald Krystal, William G. Kerr, Noriko Toyama-Sorimachi and Andrew P. Makrigiannis

J Immunol April 15, 2013, 190 (8) 3994-4004; DOI: https://doi.org/10.4049/jimmunol.1200873
Open Access
PU.1-Dependent Transcriptional Regulation of miR-142 Contributes to Its Hematopoietic Cell–Specific Expression and Modulation of IL-6
Author Choice Article

Yaping Sun, John Sun, Toubai Tomomi, Evelyn Nieves, Nathan Mathewson, Hiroya Tamaki, Rebecca Evers and Pavan Reddy

J Immunol April 15, 2013, 190 (8) 4005-4013; DOI: https://doi.org/10.4049/jimmunol.1202911
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Bcl6 Expressing Follicular Helper CD4 T Cells Are Fate Committed Early and Have the Capacity To Form Memory
Youn Soo Choi, Jessica A. Yang, Isharat Yusuf, Robert J. Johnston, Jason Greenbaum, Bjoern Peters and Shane Crotty

J Immunol April 15, 2013, 190 (8) 4014-4026; DOI: https://doi.org/10.4049/jimmunol.1202963
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TNFR-Associated Factor 6 Regulates TCR Signaling via Interaction with and Modification of LAT Adapter
Ji-Ji Xie, Jia-Qi Liang, Liang-Hui Diao, Amnon Altman and Yingqiu Li

J Immunol April 15, 2013, 190 (8) 4027-4036; DOI: https://doi.org/10.4049/jimmunol.1202742
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Essential Roles of K63-Linked Polyubiquitin-Binding Proteins TAB2 and TAB3 in B Cell Activation via MAPKs
Daisuke Ori, Hiroki Kato, Hideki Sanjo, Sarang Tartey, Takashi Mino, Shizuo Akira and Osamu Takeuchi

J Immunol April 15, 2013, 190 (8) 4037-4045; DOI: https://doi.org/10.4049/jimmunol.1300173
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Calcitonin Gene-Related Peptide and Cyclic Adenosine 5′-Monophosphate/Protein Kinase A Pathway Promote IL-9 Production in Th9 Differentiation Process
Norihisa Mikami, Yayoi Miyagi, Kaori Sueda, Miku Takatsuji, So-ichiro Fukada, Hiroshi Yamamoto and Kazutake Tsujikawa

J Immunol April 15, 2013, 190 (8) 4046-4055; DOI: https://doi.org/10.4049/jimmunol.1203102

IMMUNE SYSTEM DEVELOPMENT

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Stepwise Epigenetic and Phenotypic Alterations Poise CD8⁺ T Cells To Mediate Airway Hyperresponsiveness and Inflammation
Yi Jia, Katsuyuki Takeda, Junyan Han, Anthony Joetham, Roland A. Marcus, Joseph J. Lucas, Brian P. O’Connor and Erwin W. Gelfand

J Immunol April 15, 2013, 190 (8) 4056-4065; DOI: https://doi.org/10.4049/jimmunol.1202640

IMMUNOGENETICS

Open Access
Next-Generation Sequencing Identifies MicroRNAs that Associate with Pathogenic Autoimmune Neuroinflammation in Rats
Author Choice Article

Petra Bergman, Tojo James, Lara Kular, Sabrina Ruhrmann, Tatiana Kramarova, Anders Kvist, Gordana Supic, Alan Gillett, Andor Pivarcsi and Maja Jagodic

J Immunol April 15, 2013, 190 (8) 4066-4075; DOI: https://doi.org/10.4049/jimmunol.1200728
Open Access
Coordinated Changes in DNA Methylation in Antigen-Specific Memory CD4 T Cells
Author Choice Article

Shin-ichi Hashimoto, Katsumi Ogoshi, Atsushi Sasaki, Jun Abe, Wei Qu, Yoichiro Nakatani, Budrul Ahsan, Kenshiro Oshima, Francis H. W. Shand, Akio Ametani, Yutaka Suzuki, Shuichi Kaneko, Takashi Wada, Masahira Hattori, Sumio Sugano, Shinichi Morishita and Kouji Matsushima

J Immunol April 15, 2013, 190 (8) 4076-4091; DOI: https://doi.org/10.4049/jimmunol.1202267

IMMUNOTHERAPY AND VACCINES

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Immunization with Escherichia coli Outer Membrane Vesicles Protects Bacteria-Induced Lethality via Th1 and Th17 Cell Responses
Oh Youn Kim, Bok Sil Hong, Kyong-Su Park, Yae Jin Yoon, Seng Jin Choi, Won Hee Lee, Tae-Young Roh, Jan Lötvall, Yoon-Keun Kim and Yong Song Gho

J Immunol April 15, 2013, 190 (8) 4092-4102; DOI: https://doi.org/10.4049/jimmunol.1200742
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Polyinosinic-Polycytidylic Acid Is the Most Effective TLR Adjuvant for SIV Gag Protein–Induced T Cell Responses In Nonhuman Primates
Haesun Park, Lauren Adamson, Tae Ha, Karl Mullen, Shoko I. Hagen, Arys Nogueron, Andrew W. Sylwester, Michael K. Axthelm, Al Legasse, Michael Piatak, Jeffrey D. Lifson, Juliana M. McElrath, Louis J. Picker and Robert A. Seder

J Immunol April 15, 2013, 190 (8) 4103-4115; DOI: https://doi.org/10.4049/jimmunol.1202958
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Enhanced Immunogenicity of a Tricomponent Mannan Tetanus Toxoid Conjugate Vaccine Targeted to Dendritic Cells via Dectin-1 by Incorporating β-Glucan
Tomasz Lipinski, Amira Fitieh, Joëlle St. Pierre, Hanne L. Ostergaard, David R. Bundle and Nicolas Touret

J Immunol April 15, 2013, 190 (8) 4116-4128; DOI: https://doi.org/10.4049/jimmunol.1202937

INFECTIOUS DISEASE AND HOST RESPONSE

Open Access
Candida albicans Primes TLR Cytokine Responses through a Dectin-1/Raf-1–Mediated Pathway
Author Choice Article

Daniela C. Ifrim, Leo A. B. Joosten, Bart-Jan Kullberg, Liesbeth Jacobs, Trees Jansen, David L. Williams, Neil A. R. Gow, Jos W. M. van der Meer, Mihai G. Netea and Jessica Quintin

J Immunol April 15, 2013, 190 (8) 4129-4135; DOI: https://doi.org/10.4049/jimmunol.1202611
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An Extracellular Matrix–Based Mechanism of Rapid Neutrophil Extracellular Trap Formation in Response to Candida albicans
Angel S. Byrd, Xian M. O’Brien, Courtney M. Johnson, Liz M. Lavigne and Jonathan S. Reichner

J Immunol April 15, 2013, 190 (8) 4136-4148; DOI: https://doi.org/10.4049/jimmunol.1202671
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Fibrin Facilitates Both Innate and T Cell–Mediated Defense against Yersinia pestis
Deyan Luo, Jr-Shiuan Lin, Michelle A. Parent, Isis Mullarky-Kanevsky, Frank M. Szaba, Lawrence W. Kummer, Debra K. Duso, Michael Tighe, Jim Hill, Andras Gruber, Nigel Mackman, David Gailani and Stephen T. Smiley

J Immunol April 15, 2013, 190 (8) 4149-4161; DOI: https://doi.org/10.4049/jimmunol.1203253
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A New Model for CD8⁺ T Cell Memory Inflation Based upon a Recombinant Adenoviral Vector
Beatrice Bolinger, Stuart Sims, Geraldine O’Hara, Catherine de Lara, Elma Tchilian, Sonja Firner, Daniel Engeler, Burkhard Ludewig and Paul Klenerman

J Immunol April 15, 2013, 190 (8) 4162-4174; DOI: https://doi.org/10.4049/jimmunol.1202665
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Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice
Melissa J. Grimm, R. Robert Vethanayagam, Nikolaos G. Almyroudis, Carly G. Dennis, A. Nazmul H. Khan, Anthony C. D’Auria, Kelly L. Singel, Bruce A. Davidson, Paul R. Knight, Timothy S. Blackwell, Tobias M. Hohl, Michael K. Mansour, Jatin M. Vyas, Marc Röhm, Constantin F. Urban, Tiina Kelkka, Rikard Holmdahl and Brahm H. Segal

J Immunol April 15, 2013, 190 (8) 4175-4184; DOI: https://doi.org/10.4049/jimmunol.1202800
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Liver Sinusoidal Endothelial Cell Lectin Inhibits CTL-Dependent Virus Clearance in Mouse Models of Viral Hepatitis
Biao Liu, Min Wang, Xiaowen Wang, Dianyuan Zhao, Di Liu, Jing Liu, Pei-Jer Chen, Dongliang Yang, Fuchu He and Li Tang

J Immunol April 15, 2013, 190 (8) 4185-4195; DOI: https://doi.org/10.4049/jimmunol.1203091
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IL-1β Promotes Antimicrobial Immunity in Macrophages by Regulating TNFR Signaling and Caspase-3 Activation
Pushpa Jayaraman, Isabel Sada-Ovalle, Tomoyasu Nishimura, Ana C. Anderson, Vijay K. Kuchroo, Heinz G. Remold and Samuel M. Behar

J Immunol April 15, 2013, 190 (8) 4196-4204; DOI: https://doi.org/10.4049/jimmunol.1202688
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Altered T-bet Dominance in IFN-γ–Decoupled CD4⁺ T Cells with Attenuated Cytokine Storm and Preserved Memory in Influenza
Avijit Dutta, Shi-Chuen Miaw, Jhang-Sian Yu, Tse-Ching Chen, Chun-Yen Lin, Yung-Chang Lin, Chia-Shiang Chang, Yueh-Chia He, Sheng-Hao Chuang, Ming-I Yen and Ching-Tai Huang

J Immunol April 15, 2013, 190 (8) 4205-4214; DOI: https://doi.org/10.4049/jimmunol.1202434

INNATE IMMUNITY AND INFLAMMATION

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Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans
Heike Unnewehr, Daniel Rittirsch, J. Vidya Sarma, Firas Zetoune, Michael A. Flierl, Mario Perl, Stephanie Denk, Manfred Weiss, Marion E. Schneider, Peter N. Monk, Thomas Neff, Michael Mihlan, Holger Barth, Florian Gebhard, Peter A. Ward and Markus Huber-Lang

J Immunol April 15, 2013, 190 (8) 4215-4225; DOI: https://doi.org/10.4049/jimmunol.1200534
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Selective Impairment of P2Y Signaling by Prostaglandin E₂ in Macrophages: Implications for Ca²⁺-Dependent Responses
Paqui G. Través, María Pimentel-Santillana, Luz María G. Carrasquero, Raquel Pérez-Sen, Esmerilda G. Delicado, Alfonso Luque, Manuel Izquierdo, Paloma Martín-Sanz, María Teresa Miras-Portugal and Lisardo Boscá

J Immunol April 15, 2013, 190 (8) 4226-4235; DOI: https://doi.org/10.4049/jimmunol.1203029
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Monocyte ADAM17 Promotes Diapedesis during Transendothelial Migration: Identification of Steps and Substrates Targeted by Metalloproteinases
Yoshiaki Tsubota, Jeremy M. Frey, Phillip W. L. Tai, Robert E. Welikson and Elaine W. Raines

J Immunol April 15, 2013, 190 (8) 4236-4244; DOI: https://doi.org/10.4049/jimmunol.1300046
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Fas-Mediated Inflammatory Response in Listeria monocytogenes Infection
Ryosuke Uchiyama, Shin Yonehara and Hiroko Tsutsui

J Immunol April 15, 2013, 190 (8) 4245-4254; DOI: https://doi.org/10.4049/jimmunol.1203059
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CD62L Is Critical for Maturation and Accumulation of Murine Hepatic NK Cells in Response to Viral Infection
Hui Peng, Rui Sun, Ling Tang, Haiming Wei and Zhigang Tian

J Immunol April 15, 2013, 190 (8) 4255-4262; DOI: https://doi.org/10.4049/jimmunol.1202395
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Solute Carrier 11A1 Is Expressed by Innate Lymphocytes and Augments Their Activation
Jodi F. Hedges, Emily Kimmel, Deann T. Snyder, Maria Jerome and Mark A. Jutila

J Immunol April 15, 2013, 190 (8) 4263-4273; DOI: https://doi.org/10.4049/jimmunol.1200732
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TNF-Induced Death Signaling Triggers Alveolar Epithelial Dysfunction in Acute Lung Injury
Brijesh V. Patel, Michael R. Wilson, Kieran P. O’Dea and Masao Takata

J Immunol April 15, 2013, 190 (8) 4274-4282; DOI: https://doi.org/10.4049/jimmunol.1202437
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Profibrotic Activities for Matrix Metalloproteinase-8 during Bleomycin-Mediated Lung Injury
Vanessa J. Craig, Pablo A. Quintero, Susanne E. Fyfe, Avignat S. Patel, Martin D. Knolle, Lester Kobzik and Caroline A. Owen

J Immunol April 15, 2013, 190 (8) 4283-4296; DOI: https://doi.org/10.4049/jimmunol.1201043
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A Novel Small-Molecule Enantiomeric Analogue of Traditional (−)-Morphinans Has Specific TLR9 Antagonist Properties and Reduces Sterile Inflammation-Induced Organ Damage
Rafaz Hoque, Ahmad Farooq, Ahsan Malik, Bobby N. Trawick, David W. Berberich, Joseph P. McClurg, Karen P. Galen and Wajahat Mehal

J Immunol April 15, 2013, 190 (8) 4297-4304; DOI: https://doi.org/10.4049/jimmunol.1202184
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α1β1 Integrin-Mediated Adhesion Inhibits Macrophage Exit from a Peripheral Inflammatory Lesion
Henry M. Becker, Jacob Rullo, Mian Chen, Magar Ghazarian, Sungho Bak, Haiyan Xiao, John B. Hay and Myron I. Cybulsky

J Immunol April 15, 2013, 190 (8) 4305-4314; DOI: https://doi.org/10.4049/jimmunol.1202097
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Impact of Immune Complex Size and Glycosylation on IgG Binding to Human FcγRs
Anja Lux, Xiaojie Yu, Chris N. Scanlan and Falk Nimmerjahn

J Immunol April 15, 2013, 190 (8) 4315-4323; DOI: https://doi.org/10.4049/jimmunol.1200501
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Signaling through Purinergic Receptors for ATP Induces Human Cutaneous Innate and Adaptive Th17 Responses: Implications in the Pathogenesis of Psoriasis
Meaghan E. Killeen, Laura Ferris, Erine A. Kupetsky, Louis Falo and Alicia R. Mathers

J Immunol April 15, 2013, 190 (8) 4324-4336; DOI: https://doi.org/10.4049/jimmunol.1202045
Open Access
Antisense Oligonucleotide Treatment Enhances the Recovery of Acute Lung Injury through IL-10–Secreting M2-like Macrophage-Induced Expansion of CD4⁺ Regulatory T Cells
Author Choice Article

Zhongliang Guo, Zhenke Wen, Andong Qin, Ya Zhou, Zhenyuan Liao, Zhongmin Liu, Yongjie Liang, Tao Ren and Lin Xu

J Immunol April 15, 2013, 190 (8) 4337-4348; DOI: https://doi.org/10.4049/jimmunol.1203233
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Cxcl8 (IL-8) Mediates Neutrophil Recruitment and Behavior in the Zebrafish Inflammatory Response
Sofia de Oliveira, Constantino C. Reyes-Aldasoro, Sergio Candel, Stephen A. Renshaw, Victoriano Mulero and Ângelo Calado

J Immunol April 15, 2013, 190 (8) 4349-4359; DOI: https://doi.org/10.4049/jimmunol.1203266

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Glucocorticoids Induce Effector T Cell Depolarization via ERM Proteins, Thereby Impeding Migration and APC Conjugation
Nora Müller, Henrike J. Fischer, Denise Tischner, Jens van den Brandt and Holger M. Reichardt

J Immunol April 15, 2013, 190 (8) 4360-4370; DOI: https://doi.org/10.4049/jimmunol.1201520
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Distinct Binding Affinities of Mac-1 and LFA-1 in Neutrophil Activation
Ning Li, Debin Mao, Shouqin Lü, Chunfang Tong, Yan Zhang and Mian Long

J Immunol April 15, 2013, 190 (8) 4371-4381; DOI: https://doi.org/10.4049/jimmunol.1201374

TRANSPLANTATION

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Potential Contribution of a Novel Tax Epitope–Specific CD4⁺ T Cells to Graft-versus-Tax Effect in Adult T Cell Leukemia Patients after Allogeneic Hematopoietic Stem Cell Transplantation
Yotaro Tamai, Atsuhiko Hasegawa, Ayako Takamori, Amane Sasada, Ryuji Tanosaki, Ilseung Choi, Atae Utsunomiya, Yasuhiro Maeda, Yoshihisa Yamano, Tetsuya Eto, Ki-Ryang Koh, Hirohisa Nakamae, Youko Suehiro, Koji Kato, Shigeki Takemoto, Jun Okamura, Naokuni Uike and Mari Kannagi

J Immunol April 15, 2013, 190 (8) 4382-4392; DOI: https://doi.org/10.4049/jimmunol.1202971

TUMOR IMMUNOLOGY

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Adaptive Immunity Does Not Strongly Suppress Spontaneous Tumors in a Sleeping Beauty Model of Cancer
Laura M. Rogers, Alicia K. Olivier, David K. Meyerholz and Adam J. Dupuy

J Immunol April 15, 2013, 190 (8) 4393-4399; DOI: https://doi.org/10.4049/jimmunol.1203227
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Differential Effects of Phenethyl Isothiocyanate and D,L-Sulforaphane on TLR3 Signaling
Jianzhong Zhu, Arundhati Ghosh, Elizabeth M. Coyle, Joomin Lee, Eun-Ryeong Hahm, Shivendra V. Singh and Saumendra N. Sarkar

J Immunol April 15, 2013, 190 (8) 4400-4407; DOI: https://doi.org/10.4049/jimmunol.1202093
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Epithelial–Mesenchymal Transition Induces an Antitumor Immune Response Mediated by NKG2D Receptor
Alejandro López-Soto, Leticia Huergo-Zapico, José Alberto Galván, Luis Rodrigo, Antonio García de Herreros, Aurora Astudillo and Segundo Gonzalez

J Immunol April 15, 2013, 190 (8) 4408-4419; DOI: https://doi.org/10.4049/jimmunol.1202950
Open Access
Inflammation Induced by MMP-9 Enhances Tumor Regression of Experimental Breast Cancer
Author Choice Article

Karin Söderlund Leifler, Susanne Svensson, Annelie Abrahamsson, Christina Bendrik, Jennifer Robertson, Jack Gauldie, Anna-Karin Olsson and Charlotta Dabrosin

J Immunol April 15, 2013, 190 (8) 4420-4430; DOI: https://doi.org/10.4049/jimmunol.1202610

CORRECTIONS

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Correction: Haemophilus influenzae Surface Fibrils Contribute to Serum Resistance by Interacting with Vitronectin
T. Hallström, E. Trajkovska, A. Forsgren and K. Riesbeck

J Immunol April 15, 2013, 190 (8) 4431; DOI: https://doi.org/10.4049/jimmunol.1390012
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Correction: Antigen aggregation decides the fate of the allergic immune response
N. Zaborsky, M. Brunner, M. Wallner, M. Himly, T. Karl, R. Schwarzenbacher, F. Ferreira and G. Achatz

J Immunol April 15, 2013, 190 (8) 4432; DOI: https://doi.org/10.4049/jimmunol.1390013
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Correction: The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions
C. Kim, C. C. Marchal, J. Penninger and M. C. Dinauer

J Immunol April 15, 2013, 190 (8) 4433; DOI: https://doi.org/10.4049/jimmunol.1390015

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IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

ALLERGY AND OTHER HYPERSENSITIVITIES

ANTIGEN RECOGNITION AND RESPONSES

AUTOIMMUNITY

CLINICAL AND HUMAN IMMUNOLOGY

IMMUNE REGULATION

IMMUNE SYSTEM DEVELOPMENT

IMMUNOGENETICS

IMMUNOTHERAPY AND VACCINES

INFECTIOUS DISEASE AND HOST RESPONSE

INNATE IMMUNITY AND INFLAMMATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

TRANSPLANTATION

TUMOR IMMUNOLOGY

CORRECTIONS

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