On the cover: Absence of the principal PGE2 synthesizing enzyme permits marked remodeling of the pulmonary vasculature in response to dust mite allergen-induced lung inflammation. Image shows a ×200 magnification of a section of the lung of a ptges−/− mouse stained with an antibody against α-smooth muscle actin. Lundequist, A., S. N. Nallamshetty, W. Xing, C. Feng, T. M. Laidlaw, S. Uematsu, S. Akira, and J. A. Boyce. 2010. Prostaglandin E2 exerts homeostatic regulation of pulmonary vascular remodeling in allergic airway inflammation. J. Immunol. 184: 433–441.