Activation of Human Peripheral IgM⁺ B Cells Is Transiently Inhibited by BCR-Independent Aggregation of FcRIIB

Data Supplement

Files in this Data Supplement:

• Supplemental Figure Legend (PDF, 14.6 Kb)
  
• Figure S1 (PDF, 204 Kb)
  - Comparative binding of polyclonal F(ab')₂ rabbit anti-human IgG and IgM antibodies to human surface IgG⁺ or IgM⁺ B cells.
• Figure S2 (PDF, 103 Kb)
  - Lack of binding of polyclonal F(ab')₂ rabbit anti-human IgM antibodies to mouse surface IgG⁺ cells.
• Figure S3 (PDF, 548 Kb)
  - Polyclonal F(ab')₂ rabbit anti-human IgM antibodies do not cross-react with mouse and human IgG even at high doses.
• Figure S4 (PDF, 373 Kb)
  - Polyclonal F(ab')₂ rabbit anti-human IgM antibodies do not induce purified IgG⁺ human B lymphocytes proliferation.
• Figure S5 (PDF, 151 Kb)
  - Kinetics of inhibition of BCR-mediated B cell proliferation by the sole aggregation of FcγRIIB1.