Oncostatin M-Induced and Constitutive Activation of the JAK2/STAT5/CIS Pathway Suppresses CCL1, but Not CCL7 and CCL8, Chemokine Expression
J Immunol Hintzen et al.
181: 7341
Supplemental Figure S2 (PDF, 210 Kb) -
A, HDFswere preincubatedwith 10μM U0126, SB202190, SP600125 or AG490 for 30 min and subsequentlystimulated with OSM (20 ng/ml)...
Supplemental Figure S3 (PDF, 82 Kb) -
HDFswere pretreated with 10μM AG490 for 30 min, exposed to 20 ng/ml OSM for 3 h and then the protein amounts of CCL1 or CCL8 in culture supernatants were measured by ELISA. Data are expressed as mean ±S.D. (n = 4). * = p< 0.05 versus control...
Supplemental Figure S5 (PDF, 81.9 Kb) -
HELswere transfectedwith control or CIS siRNA, preincubatedwith 1 μMJI-1 for 12 h and then stimulated 10 ng/ml IL-1βor 20 ng/ml OSM for 3 h...