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The Host Environment Regulates the Function of CD8
+
Graft-versus-Host-Reactive Effector Cells
J Immunol Chakraverty et al. 181: 6820
Data Supplement
Files in this Data Supplement:
Supplemental Data Legend (PDF, 59.4 Kb)
Supplemental Figure S1 (PDF, 86.3 Kb)
- No deficiency of IFN-γ synthesis by donor CD8 cells in MC following stimulation with PMA/ionomycin.
Supplemental Figure S2 (PDF, 104 Kb)
- Reduced effector differentiation and cytotoxic functions of donor CD8 cells activated in B6 + BDF1 → BDF1 MC compared to BDF1 TBI-allo mice.
Supplemental Figure S3 (PDF, 114 Kb)
- Irradiation and TLR-induced inflammation lead to reductions in numbers of CD4+Foxp3+ cells in spleen.
Supplemental Figure S4 (PDF, 39.1 Kb)
- Low-dose irradiation is sufficient to generate anti-host IFN-γ
high
CTL.
Supplemental Tables S1-S2 (PDF, 63.2 Kb)
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