Data Supplement

Files in this Data Supplement:

• Supplementary Methods (PDF, 103 Kb)
  
• Supplementary Figure 1 (PDF, 127 Kb)
  - Changes in the percentages of CD4+ CD25+ T-cells in ONTAK treated animals.
• Supplementary Figure 2 (PDF, 277 Kb)
  - Dynamics of FOX-P3 in ONTAK treated animals.
• Supplementary Figure 3 (PDF, 121 Kb)
  - Comparison of Treg function in Ontaktreated vs untreated SIVagm-infected AGMs (CFSE staining).
• Supplementary Figure 4 (PDF, 228 Kb)
  - Changes in the percentages (a) and absolute counts (b) of peripheral CD4⁺ T cells in ONTAK treated animals.
• Supplementary Figure 5 (PDF, 121 Kb)
  - Dynamics of CD28negCD95⁺ CD4⁺ Tcells (effector memory cells) in Ontak-treated AGMs.
• Supplementary Figure 6 (PDF, 124 Kb)
  - Significant increases of the levels of CCR5 mRNA were observed after Ontak administration, confirming the increase of immune activation after the ONTAK treatment.
• Supplementary Table 1 (PDF, 65.7 Kb)
  - Changes in the CD4⁺ T cells and T regulatory cells (defined as CD4⁺ CD25⁺ T cells and CD4⁺ CD25⁺ Fox-P3⁺ T cells) in Ontak-treated AGMs.