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Correction for Iizuka et al., J Immunol 179 (2) 1122-1128.
The Journal of Immunology, 2007, 179, 6368
Copyright © 2007 by The American Association of Immunologists, Inc.
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Protection from lethal infection by adoptive transfer of CD8 T cells genetically engineered to express virus-specific innate immune receptor.

K. Iizuka, C. Nakajima, Y.-M. Iizuka, M. Takase, T. Kato, S. Noda, K. Tanaka and O. Kanagawa

Iizuka, K., C. Nakajima, Y.-M. Iizuka, M. Takase, T. Kato, S. Noda, K. Tanaka, and O. Kanagawa. 2007. Protection from lethal infection by adoptive transfer of CD8 T cells genetically engineered to express virus-specific innate immune receptor. J. Immunol. 179: 1122–1128 .

In Fig. 3, A–C, the legend, and Fig. 4A and B, there are errors in the triangles depicting CD8 T cells expressing Ly49HZ. The corrected Fig. 3, Fig. 3 legend, and Fig. 4 are shown below.


Figure 3
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  		FIGURE 3. Protection of BALB/c mice from lethal MCMV infection by CD8 T cells expressing Ly49H-CD3{zeta} chimeric receptor and establishment of memory response. A, A total of 5 x 107 CD8 T cells either expressing Ly49HZ receptor ({blacktriangleup}), Ly49Hcyto-del ({triangleup}), or none ({blacksquare}) were injected into BALB/c mice (10 mice per group). Within 1 h of T cell transfer, the mice were infected with MCMV (4 x 106 pfu/mouse) and monitored for survival. B, Mice were infected with MCMV (4 x 106 pfu/mouse). Seventy-two hours after the infection, 5 x 107 CD8 T cells either expressing Ly49HZ receptor ({blacktriangleup}) or no cells ({blacksquare}) were injected into BALB/c mice (10 mice per group). C, Ten BALB/c mice that had been protected from initial MCMV infection by Ly49HZ-expressing CD8 T cells ({blacktriangleup}) were rechallenged with MCMV 40 days after initial infection without further CD8 T cell transfusion. As a control, naive uninfected BALB/c mice ({blacksquare}) (five mice per group) were infected with the same amount of virus. Representative data from two experiments are shown. D, Spleen cells from mice treated identically as in Fig. 3C ({blacktriangleup}) were analyzed for the presence of GFP-positive CD8 T cells 10 days after rechallenge. Representative data from three mice are shown.

 

Figure 4
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  		FIGURE 4.
 





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