Correction
for Kelly et al., J Immunol 168 (2) 597-603.
The Journal of Immunology, 2007,
179,
8569
Copyright © 2007 by The American Association of Immunologists, Inc.
IL-2 and related cytokines can promote T cell survival by activating AKT
E. Kelly,
A. Won,
Y. Refaeli and
L. Van Parijs
Kelly, E., A. Won, Y. Refaeli, and L. Van Parijs. 2002. IL-2 and related cytokines can promote T cell survival by activating AKT. J. Immunol. 168: 597–603
.
Erin Kelly, Angela Won, and Yosef Refaeli wish to retract Fig. 5B. The retraction involves the part of the paper claiming to show that expression of AKT in Ag-primed T cells leads to up-regulation of Bcl-2 but not cFLIP. This result was used to support the idea that Akt blocks apoptosis of Ag-primed T cells following growth factor withdrawal but not following death receptor activation. Kelly, Won, and Refaeli have no reason to believe that the other results and interpretations in this paper need to be corrected or retracted. This retraction follows an investigation by the Massachusetts Institute of Technology into scientific misconduct by Dr. Luk Van Parijs, the corresponding author of the paper, that found the retracted figure had been falsified or fabricated. The investigation also found that Dr. Van Parijs was solely responsible for the scientific misconduct that resulted in the falsified or fabricated data or conclusions in this paper.
