Genome-Wide Analysis of Gene Expression in T Cells to Identify Targets of the NF-B Transcription Factor c-Rel
J Immunol Bunting et al.
178: 7097
Data Supplement
Files in this Data Supplement:
Supplemental Table (PDF, 481 Kb) -
1A: Primer sets used for QPCR analysis of genes affected by c-Rel deletion and/or over-expression.
1B: Genes identified by microarray analysis of CD3/CD28-activated CD4+ T
cells isolated from wt and c-Rel-/- mice that are affected by c-Rel deletion in three independent
experiments.
1C: Genes identified by microarray analysis of NS and P/I-stimulated EL-4 T
cells transfected with an empty vector or a c-Rel over-expression plasmid whose expression is increased greater than or equal to 5-fold in c-Rel over-expressing cells in two independent experiments.
1D: Average fold changes in gene expression in NS and P/I-stimulated
vector-transfected and c-Rel-over-expressing EL-4 cells (compared to NS vector-transfected cells) as measured by QPCR.
1E: Average fold changes in gene expression in NS and CD3/CD28- or P/Istimulated wt and c-Rel-/- CD4+ T cells (compared to wt NS cells) as measured by QPCR.