Correction
for Chan et al., J Immunol 176 (8) 4852-4860.
The Journal of Immunology, 2006, 176: 7132.
Copyright © 2006 by The American Association of Immunologists, Inc.
Nuclear magnetic resonance structure-based epitope mapping and modulation of dust mite group 13 allergen as a hypoallergen
S. L. Chan,
S. T. Ong,
S. Y. Ong,
F. T. Chew and
Y. K. Mok
Chan, S. L., S. T. Ong, S. Y. Ong, F. T. Chew, and Y. K. Mok. 2006. Nuclear magnetic resonance structure-based epitope mapping and modulation of dust mite group 13 allergen as a hypoallergen. J. Immunol. 176: 48524860
.
In Table II, the epitope residues cited for Equ c 1 are incorrect. The corrected table is shown below.
In Discussion, in the last sentence of the fifth paragraph, inclusion of Equ c 1 and the respective citation (Ref. 31) are incorrect. The second sentence of the sixth paragraph has also been revised. The corrected sentences are shown below.
In addition to the group 13 dust mite allergen, other studies have also used a similar approach to generate hypoallergens by mutating specific surface residues on allergens, including Bet v 1 (10) and Hev b 6.02 (30).
In Equ c 1, regions of the protein mapped as IgE binding epitopes consist mostly of charged and polar residues.