Files in this Data Supplement:

• Supplemental Table (Microsoft Excel, 94 KB) - consists of:
  
  
  • Table 1. Temperature (ºF)
    Body temperature was monitored before, during, and after each infusion of TRX1 or saline at 5 min intervals. Pre is the temperature reading 5 min before the start of infusion; +30 min is the temperature reading 30 min after the start of the infusion (approximately half way through the procedure); and Post is the temperature reading 5 min after all antibody or saline was delivered.
    
    
  • Table 2. Blood Pressure (mmHg)
    Blood pressure (BP) was monitored before, during, and after each infusion of TRX1 or saline at 5 min intervals. Pre is the BP reading 5 min before the start of infusion; +30 min is the BP reading 30 min after the start of the infusion (approximately half way through the procedure); and Post is the BP reading 5 min after all antibody or saline was delivered.
    
    
  • Table 3. Weight (Kg)
    Body weight was determined for all animals prior to each infusion (TRX1 or saline), immunization and challenge.
    
    
  • Table 4. Viral Serology (Titer)
    Viral antibody titers were determined by Esoterix, Inc. (San Antonio, TX) using a modified version of the rapid dot-immunobinding assay [Heberling, R.L. and Kalter, S.S. Rapid dot-immunobinding assay on nitrocellulose for viral antibodies. 1986. J. Clin. Microbiol. 23:109]. Titer is defined as the reciprocal of the serum dilution with a signal intensity greater than the negative control.
    
    
  • Table 5A and 5B. Antibody Titers to Equine Ig
    Baboon anti-globulin titers to equine Ig were determined by ELISA as described in Methods. Titer is defined as the reciprocal of the serum dilution resulting in an OD value equivalent to twice the OD value of a postive control baboon serum diluted 1:25,000.