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Processing of Exogenous Antigens for Presentation by Class I MHC Molecules Involves Post-Golgi Peptide Exchange Influenced by Peptide-MHC Complex Stability and Acidic pH

Peter J. Chefalo and Clifford V. Harding. Processing of Exogenous Antigens for Presentation by Class I MHC Molecules Involves Post-Golgi Peptide Exchange Influenced by Peptide-MHC Complex Stability and Acidic pH. The Journal of Immunology 2001;167:1274–1282 .

An error was made in describing the protocol used for experiments shown in Figs. 5, 6, and 7. Text in the Materials and Methods and Results sections, along with figure legends for Figs. 5, 6, and 7 implied that antigenic readout peptide was only added subsequent to the incubation of macrophages in citrate-buffered saline at varying pH, but peptide was actually added at the indicated concentrations both during the incubation in citrate-buffered saline at varying pH and in the subsequent incubation for 2 h in normal medium. This correction does not change the conclusion of the paper, but is important for executing future studies.

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Chefalo, P. J. Articles by Harding, C. V. Search for Related Content PubMed Articles by Chefalo, P. J. Articles by Harding, C. V.