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| Introduction |
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The authors found in Figure 5 that wild-type EGFP-CIITA had been used inadvertently for immunofluorescence localization instead of the L469P mutant. They found the bona fide CIITA-L469P is localized predominantly in the cytoplasm; however, it also transits through the nucleus since it shows strong nuclear accumulation after leptomycin treatment. Residual nuclear localization of CIITA-L469P is also found by biochemical analysis of the patient fibroblasts subcellular fractions and is supported by the residual transactivation potential of CIITA-L469P. The main findings and conclusions of the paper remain unchanged.
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