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The Journal of Immunology, 1966, 97: 126-130.
Copyright © 1966 by The American Association of Immunologists, Inc.

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Relationship of Interferon-Like Inhibitor Production to Rous Sarcoma Virus Growth and Tumor Formation in Chicks

Elizabeth E. Force1 and Richard C. Stewart

From the Research and Development Division, Smith Kline & French Laboratories, Philadelphia, Pennsylvania

Abstract

An interferon-like inhibitor was found in Rous sarcoma virus (RSV)-infected wing web tissues of the chick prior to the appearance of infectious RSV, tumor formation, viremia and circulating antibody. This inhibitor possessed several of the properties generally ascribed to interferon.

Footnotes

1 Present address: Institute for Cooperative Research, University of Pennsylvania, Philadelphia, Pennsylvania.







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