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The Journal of Immunology, 1966, 96: 646-649.
Copyright © 1966 by The American Association of Immunologists, Inc.
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Serologic Features of Mycoplasmal Arthritis in Swine1

Kimmo Aho2, William P. Switzer, Robert W. Lightfoot, Jr.3 and Charles L. Christian4

From the Department of Medicine, Columbia University College of Physicians and Surgeons, The Edward Daniels Faulkner Arthritis Clinic of the Presbyterian Hospital of the City of New York, and the Veterinary Medical Research Institute, College of Veterinary Medicine, Iowa State University of Science and Technology, Ames, Iowa

Abstract

All of 7 sera from swine with Mycoplasma granularum arthritis contained warm-type anti-human O agglutinins in higher titers than 9 control sera (healthy mycoplasma-free swine) and a swine serum pool. Cross-absorptions indicated that the agglutinins were not monospecific. Four of 7 sera of arthritic swine contained anti-rabbit {gamma}-globulins in titers four-fold higher than the control sera. No reactivity with swine {gamma}-globulin could be demonstrated. Both the anti-group O agglutinins and the anti-rabbit {gamma}-globulins had the sedimenting properties of macroglobulins.

Footnotes

1 This investigation was supported in part by Public Health Service Traineeship T1 AM 5040-09 from the National Institute of Arthritis and Metabolic Diseases, United States Public Health Service.

2 International Fellow 1-F05-TW-798, Office of International Research, National Institutes of Health, Bethesda, Maryland.

Present address: State Serum Institute, Helsinki, Finland.

3 Send requests for reprints to Dr. Robert W. Lightfoot, Jr., 630 West 168th Street, New York, New York 10032.

4 Career Scientist, The Health Research Council of the City of New York.






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