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A Cold Agglutinin of the IgA Class¹

From the Department of Medicine, University of Rochester School of Medicine and Dentistry, and the Medical Services of the Rochester General and Strong Memorial Hospitals, Rochester, New York

Abstract

A patient with a reticulum cell sarcoma and cold agglutinin of the IgA type is reported. The cold agglutinin had a sedimentation rate of 10.5S (9.5–11.5S), indicating that it is probably a dimer of the 7-8S IgA unit. The cold agglutinin was mercaptoethanol sensitive and failed to fix complement.

Footnotes

¹ This investigation was wholly supported by Public Health Service Research Grant AM 08849-01 from the National Institute of Arthritis and Metabolic Diseases.

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