HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Kronman, B. S. Search for Related Content PubMed PubMed Citation Articles by Kronman, B. S.

Immunochemistry of Schistosoma Mansoni Cercariae

From the Department of Preventive Medicine and the Department of Pathology, New York University School of Medicine, New York, New York

Abstract

A method of antigen preparation and isolation of Schistosoma mansoni cercarial antigens is described. At least nine potentially purifiable antigenic substances from cercariae were detected. Three immunogenic components were purified and analyzed for various immunochemical properties and chemical staining reactions.

At least two different antigens of cercariae induce antibody formation in chronically infected human beings. The purified antigen I that was isolated by column chromatography reacted specifically with antibody from patients infected with Schistosoma mansoni. Whether or not one of these antigens can be utilized to induce protective immunity against natural infection is yet to be determined.