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Development of Antibodies against Aeromonas Salmonicida in Trout¹

From the Department of Bacteriology, The Pennsylvania State University, University Park, Pennsylvania

Abstract

The development of agglutinating antibody to Aeronomas salmonicida in brook and brown trout was demonstrated by a tube agglutination and a rapid slide agglutination test. Comparison of agglutinin titer development in rabbits and trout demonstrated that trout have a slow antibody response reaching maximum titer about 3 months after injection. Rabbits developed peak titers within a month after receiving the same dose of antigen. Trout immunized with a single injection of formalin-killed bacteria in a mineral oil adjuvant were protected against intraperitoneal injections of viable Aeromonas salmonicida.

Footnotes

¹ Authorized for publication April 10, 1963 as paper no. 2762 in the journal series of the Pennsylvania Agricultural Experiment Station.

² This material was taken from these submitted by George E. Krantz and Jack M. Reddecliff in partial fulfillment of the requirements for a M.S. degree from the Graduate School, The Pennsylvania State University.