HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Fahey, J. L. Articles by McLaughlin, C. Search for Related Content PubMed PubMed Citation Articles by Fahey, J. L. Articles by McLaughlin, C.

Preparation of Antisera Specific for 6.6 S -Globulins, _2A-Globulins, ₁-Macroglobulins, and for Type I and II Common -Globulin Determinants

From the Metabolism Service, National Cancer Institute, National Institutes of Health, Bethesda 14, Maryland

Abstract

Antisera reacting specifically with 6.6 S , _2A, or _1M antigenic determinants or with type I or II common -globulin determinants were prepared on the basis of current understanding of the immunochemical structure of -globulin molecules.

Purified -globulin components were necessary for the preparation and testing of specific antisera. Therefore, methods for preparing and characterizing 6.6 S -globulins, _2A-globulins, and ₁-macroglobulins from normal serum and myeloma proteins, -macroglobulins, and Bence Jones proteins from appropriate serum and urine are described.

This article has been cited by other articles:

				W. D. Terry and M. S. Roberts Antigenic Heterogeneity of Human Immunoglobulin A Proteins Science, August 26, 1966; 153(3739): 1007 - 1008. [Abstract] [PDF]

				W. D. Terry, P. A. Small Jr., and R. A. Reisfeld Electrophoretic Heterogeneity of the Polypeptide Chains of Human G-Myeloma Proteins Science, June 17, 1966; 152(3729): 1628 - 1630. [Abstract] [PDF]

				J. L. Fahey, I. Finegold, A. S. Rabson, and R. A. Manaker Immunoglobulin Synthesis in vitro by Established Human Cell Lines Science, May 27, 1966; 152(3726): 1259 - 1261. [Abstract] [PDF]

				K. R. Mcintimif, R. M. Asofsky, M. Potter, and E. L. Kuff Macroglobulin-Producing Plasma-Cell Tumor in Mice: Identification of a New Light Chain Science, October 15, 1965; 150(3694): 361 - 363. [Abstract] [PDF]

				R. I. Mishell and J. L. Fahey Molecular and Submolecular Localization of Two Isoantigens of Mouse Immunoglobulins Science, March 27, 1964; 143(3613): 1440 - 1442. [Abstract] [PDF]