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Anti-Rabies Vaccine of Tissue Culture Origin

From the U. S. Department of Health, Education & Welfare, U. S. Public Health Service, Communicable Disease Center, Atlanta, Georgia

Abstract

Formalin-inactivated vaccines of sufficient potency to satisfy the NIH standards have been prepared by concentration of rabies virus grown in hamster kidney tissue cultures. The cytopathic effect produced by tissue culture adapted rabies virus has permitted the performance of in vitro neutralization tests. Rabies virus possesses essential lipid and is probably a ribonucleic acid type virus.

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