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Effect of Thymectomy and Bursectomy on the Survival of Skin Homografts in Chickens¹

From the Department of Zoology, University of Wisconsin, Madison, Wisconsin

Abstract

1. Two strains of chickens were thymectomized and/or bursectomized at 1 to 3 days after hatching and skin homografts made at 4 or 6 days of age.

2. Thymectomy delayed skin homograft rejection, but neither steroidal or surgical bursectomy had any effect.

Footnotes

¹ A preliminary report of this work was presented at the Conference on the Thymus, sponsored by the Division of Medical Sciences, National Academy of Sciences-National Research Council and the National Foundation, at the University of Minnesota, October 29–31, 1962.

Sponsored in part by grant No. C14 A-804 (C15) from the National Institute of Arthritis and Metabolic Diseases and by Grant AI 02199-04 from the National Institutes of Health.

² This investigation was carried out during the tenure of a Predoctoral Fellowship from the Division of General Medical Sciences, United States Public Health Service.