HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Goodman, J. W. Articles by Gross, D. Search for Related Content PubMed PubMed Citation Articles by Goodman, J. W. Articles by Gross, D.

Studies on Fragments of Rabbit -Globulin¹

From the Departments of Microbiology and Medicine, University of California School of Medicine, San Francisco 22, California

Abstract

No new antigenic determinants were exposed by the enzymatic digestion of rabbit -globulin on testing with goat antisera to Fractions I and III of the papain-digested molecules.

Fractions I and II derived from papain-digested -globulin were antigenically indistinguishable and very similar but not identical to the analogous fragments resulting from digestion with pepsin, using reaction with a goat antiserum to FI (papain) as a criterion.

Antigenic determinants characteristic of rabbit -globulin were found on FI as well as on FIII.

Alanine was found to be the principal NH₂-terminal amino acid of PI and PII as well as of FI and FII.

Footnotes

¹ Supported by grants from the National Science Foundation (G-15604) and the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health (A-1229).