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From the Centre de Recherches Allergiques et Immunologiques, Hôpital Broussais, Paris, France; the Departments of Microbiology and Neurology, College of Physicians and Surgeons, Columbia University and the Neurological Institute, Presbyterian Hospital, New York and the Department of Immunochemistry, Institut Pasteur, Garches, France
Abstract
Purified human antidextran, an S = 7
-globulin, was about 1000 to 3000 times less potent in sensitizing intestine in vitro and 25 to 100 times less effective in sensitizing for passive cutaneous anaphylaxis than were the most potent human diphtheria antitoxic sera under the conditions studied. Human antitoxic sera also varied as much as 100-fold in their sensitizing capacity for intestine/µg antitoxin N.
Footnotes
1 This work was supported by Grant G-18727 from the National Science Foundation.
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