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The Journal of Immunology, 1963, 90: 17-20.
Copyright © 1963 by The American Association of Immunologists, Inc.
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Stress and Susceptibility to Viral Infection

I. Response of Adrenals, Liver, Thymus, Spleen and Peripheral Leukocyte Counts to Sound Stress1

Marcus M. Jensen2 and A. F. Rasmussen

From the Division of Virology, Department of Infectious Diseases, University of California Medical School, Los Angeles, California

Abstract

Daily 3-hr exposures to high intensity sound induced adrenal hypertrophy in mice. Peripheral leukocyte counts responded biphasically to this stressor, exhibiting a leukopenia during and a leukocytosis following the stress period on each day. Leukopenia was not seen in stressed-adrenalectomized animals.

Footnotes

1 Supported by grants from the National Institutes of Allergy and Infectious Diseases and of Mental Health, USPHS.

2 Predoctoral trainee, Mental Health Training Program, USPHS. 2M-6415. Present address: Research Service, Veterans Administration Center, Los Angeles 25, California.






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