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The Journal of Immunology, 1924, 9: 221-226.
Copyright © 1924 by The American Association of Immunologists, Inc.

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Serological Examination of a Species-Hybrid

II. Tests with Normal Agglutinins

Karl Landsteiner and James van der Scheer

From the Laboratories of The Rockefeller Institute for Medical Research, New York, N. Y.

Abstract

In the course of the investigation reported in the previouspaper we examined for the presence of agglutinins when thenormal sera of horse, donkey, and mule are tested with theblood of these same animals. The same question is dealt within a recent communication by Walsh (1). His results and conclusionsdiffer from ours in some important points.

In our opinion the subject is not largely connected with theproblem of the inheritance of species-specific properties, sincemost of the reactions observed have the character of isoagglutininreactions and have therefore nothing to do with species-differences.For the same reason these studies are related to the veryinteresting work of von Dungern and Hirschfeld (2), Epsteinand Ottenberg (3, 4), and others on the heredity, in humanbeings, of isoagglutinable substances which were found to followthe Mendelian laws.







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