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Inhibition with Simple Sugars of Hemagglutination of Red Cells Modified with Salmonella Antigens¹

From the Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts

Abstract

Oligosaccharides will inhibit hemagglutination of erythrocytes modified with antigenic extracts of salmonellas. The method described can be used to determine a possible relationship of a sugar to the structure of an antigen. The relation of certain sugar to the antigens of various salmonella serotypes was discussed.

Footnotes

¹ This investigation was carried out under the sponsorship of the Commission on Immunization of the Armed Forces Epidemiological Board and was supported by the Office of the Surgeon General, Department of the Army.

² Rockefeller Foundation Fellow in Agricultural Sciences, 1960–1961. Present address: Veterinary Research Institute, ul. Partyzantow 59, Pulawy, Poland.