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Immunochemical Studies on Blood Groups

XXVIII. Further Studies on the Oligosaccharide Determinants of Blood Group B and BP1 Specificity¹

From the Departments of Microbiology and Neurology, College of Physicians and Surgeons, Columbia University and the Neurological Institute, Presbyterian Hospital, New York

Abstract

-galactosyl 1, 3 galactose was a better inhibitor of precipitation than galactinol which in turn was better than -galactosyl-1,6-N-acetylglucosamine in both the B-anti-B and BP1-anti-BP1 systems. Since the B and BP1 determinants are distinct and since melibiose behaves quite differently as an inhibitor in these two systems, an unambiguous interpretation as to the second unit in these two determinants cannot as yet be made.

Footnotes

These studies were supported by the National Science Foundation (G-18727).