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A Precipitation Reaction Between Human Serum and a Soluble Tissue Component

From the Rockefeller Institute, New York, New York

Abstract

Certain extracts of human and animal tissues have been found to give a precipitation line with normal human serum in a gel diffusion system. This precipitation reaction results from the interaction of a basic tissue component, probably a protein, with human serum albumin. Evidence has been presented that the reaction is not of the immune type and that the interaction, which shows specificity for human albumin, is due primarily to electrostatic forces.

Footnotes

¹ Present address: University of Vermont, College of Medicine, Burlington, Vermont.