HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Myrvik, Q. N. Articles by Fariss, B. Search for Related Content PubMed PubMed Citation Articles by Myrvik, Q. N. Articles by Fariss, B.

Studies on Pulmonary Alveolar Macrophages from the Normal Rabbit: A Technique to Procure Them in a High State of Purity¹

From the Department of Microbiology, University of Virginia School of Medicine, Charlottesville, Virginia

Abstract

A technique is described for procuring large numbers of alveolar macrophages in a high state of purity, uniformity and viability from normal rabbit lungs. The macrophages can be maintained in tissue culture and are phagocytic but multiplication has not been observed. The cells undergo marked changes in volume with little loss of viability when exposed to osmotic changes. The studies are interpreted as indicating that these alveolar macrophages comprise a constitutive flora of the normal rabbit lung.

Footnotes

¹ This study was aided in part by Research Grant E-1238 C3 from the National Institutes of Health, U. S. Public Health Service, Bethesda, Maryland.

This article has been cited by other articles:

				S. Wang, R. C. Lantz, M. W. Vermeulen, G. J. Chen, V. Breceda, R. F. Robledo, A. M. Hays, S. Young, and M. L. Witten Functional alterations of alveolar macrophages subjected to smoke exposure and antioxidant lazaroids Toxicology and Industrial Health, June 1, 1999; 15(5): 464 - 469. [Abstract] [PDF]

				J Friedland, C Setton, and E Silverstein Angiotensin converting enzyme: induction by steroids in rabbit alveolar macrophages in culture Science, July 1, 1977; 197(4298): 64 - 65. [Abstract] [PDF]

				B. B. Paul, R. R. Strauss, R. J. Selvaraj, and A. J. Sbarra Peroxidase Mediated Antimicrobial Activities of Alveolar Macrophage Granules Science, August 31, 1973; 181(4102): 849 - 850. [Abstract] [PDF]

				J. Theodore, J. C. Acevedo, and E. D. Robin Implantation of Exogenous Enzymatic Activity in Isolated Alveolar Macrophages Science, December 22, 1972; 178(4067): 1302 - 1304. [Abstract] [PDF]

				H. I. Zeya and J. K. Spitznagel Cationic Protein-Bearing Granules of Polymorphonuclear Leukocytes: Separation from Enzyme-Rich Granules Science, March 7, 1969; 163(3871): 1069 - 1071. [Abstract] [PDF]