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The Journal of Immunology, 1959, 83: 632-634.
Copyright © 1959 by The American Association of Immunologists, Inc.

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The Cessation of Antibody Absorption in the Young Pig1,2,

Vaughn C. Speer, Herbert Brown, Loyd Quinn3 and Damon V. Catron

From the Department of Animal Husbandry, Iowa Agricultural and Home Economic Experiment Station, Ames, Iowa

Abstract

Eight litters of nine pigs each were employed to delineate the length of time after birth that the baby pig is capable of absorbing antibodies from orally ingested colostrum milk containing Escherichia coli antibodies. A sensitized sheep red blood cell hemagglutination test was used to detect the presence of the antibodies contained in the serum. It was found that the baby pig efficiently absorbed the E. coli antibodies at a very young age. This efficiency declined rapidly, following the first order reaction rate law, with a half-life absorption efficiency of 3 hr. Antibody absorption declined to insignificant amounts in baby pigs beyond 24 hr of age.

Footnotes

1 Journal Paper No. J-3633 of the Iowa Agricultural and Home Economics Experiment Station, ames, Iowa. Project No. 959.

2 The grant-in-aid for partial support of this project from E. R. Squibb and Sons, New Brunswick, N. J. is gratefully acknowledged.

3 Department of Bacteriology.







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