HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Hartman, J. D. Search for Related Content PubMed PubMed Citation Articles by Hartman, J. D.

The Demonstration of Two Systems Affecting Blood Leukocytes in the Hypersensitive State with Associated Inflammation¹

From the Department of Anatomy, Temple University School of Medicine, Philadelphia, Pennsylvania

Abstract

1. The in vitro agglutination of blood leukocytes has been quantitated.

2. With the quantitative technique, 2 systems affecting blood leukocytes can be demonstrated in the hypersensitive state when associated with inflammation. One system is triggered by the presence of antigen and the other functions in the presence of inflammation.

3. The basic reaction is an agglutination of the leukocytes in the presence of antigen. This reaction is accentuated in the presence of plasma taken from animals in which inflammation was present and is due to an altered reactivity of the leukocytes to the antigen leuko-agglutinating mechanism.

4. Hydrocortisone inhibits in vitro the effect of inflammation but not the effect of antigen.

Footnotes

¹ This investigation was supported by Research Grant E-1360 from the National Institute of Allergy and Infectious Diseases, Public Health Service.