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A Dangerous "Universal Donor" Detected by the Direct Matching of Bloods

From the Department of Bacteriology and Immunology, Division of Immunology, in Cornell University Medical College, and the New York Hospital

Abstract

The ideal donor for the transfusion of blood has long been known to be one of the same group as the patient. It is not always possible for these conditions to obtain, and a person of group I (Jansky) has been considered as a safe donor for any of the groups. This may not always be the case, as will be shown in this communication.

In determining blood compatibilities, two methods have been employed, the indirect and the direct. The indirect method groups the patient and prospective donors among the four recognized classes, and permits of the selection of a donor belonging to the same class as the patient, if such a donor is available. Otherwise, the "universal donor" must be resorted to.

For the proper performance of the indirect method, stock sera of Groups II and III, and a drop of the patient's citrated blood are the essential requirements.