HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Manwaring, W. H. Articles by Hospital, V. M. Search for Related Content PubMed Articles by Manwaring, W. H. Articles by Hospital, V. M.

Hepatic Reactions in Anaphylaxis

VIII. Anaphylactic Reactions in Isolated Canine Organs

From the Laboratory of Bacteriology and Experimental Pathology, Stanford University, California

Abstract

1. The isolated organs of horse serum sensitized dogs, perfused with Locke's solution containing 0.04 to 2.5 per cent horse serum, give the following reactions:

a. Lungs: Slight preliminary vasodilation, followed by a pronounced vasoconstriction. Marked edema.

b. Intestines: Distinct vasoconstriction. Marked edema.

c. Liver: Slight vasoconstriction. Slight edema.

d. Hind Quarters: Either: (1) slight vasodilation without edema or (2) slight vasoconstriction with marked edema.

2. The vasoconstriction in these organs may possibly be secondary to increased tissue pressure from edema. If so, increased specific capillary permeability must be looked upon as the dominant underlying physiological factor in these reactions.