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Observations on Induced Chronic Plasmodium Berghei Infections in White Mice

Department of Microbiology and Immunology, State University of New York College of Medicine, Brooklyn, New York

Abstract

The results of these experiments have established that chronic Plasmodium berghei infections can be induced in mice by interfering with the course of infection with Atabrine. It has been shown that these infections will persist in mice for as long as 100 days and that fatal, or non-fatal relapses may occur. Mice with chronic P. berghei infections are resistant to reinfection.