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The Journal of Immunology, 1957, 79: 259-264.
Copyright © 1957 by The American Association of Immunologists, Inc.
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The Local Response of Tissue Mast Cells to Antigen in Sensitized Mice1

Paul B. Carter2, R. D. Higginbotham and Thomas F. Dougherty

From the Department of Anatomy, University of Utah College of Medicine, Salt Lake City, Utah

Abstract

It was observed that locally injected antigen initiates a more wide-spread degranulation of local tissue mast cells in sensitized mice than in controls. The fate of the shed mast celt granules in the tissues is described and the significance of various aspects of mast cell degranulation is discussed.

Footnotes

Research supported by grants from the Department of the Army # DA-49-007-MD-130.

2 Present address: Department of Bacteriology, Utah State Agricultural College, Logan, Utah.






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