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Precipitin Production in Chickens

XVI. The Relationship of Age to Antibody Production¹

From the Department of Zoology, University of Wisconsin, Madison, Wisconsin

Abstract

1. The antibody response of chickens of various ages and different breeds to a single injection of bovine serum albumin was studied. The response is expressed as micrograms nitrogen per ml serum.

2. Statistically significant increases in response occurred between 6 and 12 weeks and between 12 and 22 weeks.

3. The average titer of 56-week-old birds was greater than the 22-week-old animals but the difference was not statistically significant.

4. Three- to 8-year-old animals gave high titered antisera.

5. There were large variations in antibody response in all age groups.

6. A statistically significant difference due to breed was found only in the 6-week-old chickens.

7. The responses of the males were not significantly different from those of the females.

Footnotes

This project was supported in part by the National Science Foundation and in part by the Research Committee of the University of Wisconsin Graduate School, from funds supplied by the Wisconsin Alumni Research Foundation.

² Present address: Department of Bacteriology and Public Health, School of Medicine, West Virginia University, Morgantown, W. Va.

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