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Serologic Comparisons with Lines of Influenza Virus Isolated and Serially Transferred in Different Experimental Hosts¹

From the Virus Laboratory, School of Public Health, Ann Arbor, Michigan

Abstract

Lines of virus derived from a single throat washing by isolation and transfers in different hosts were compared in cross tests with antisera from several species. Variations in antigenic potency and avidity for antibody were noted especially with viruses after passages in mice or in chorioallantoic membrane tissue culture.

Footnotes

¹ These studies were conducted under the auspices of the Commission on Influenza, Armed Forces Epidemiological Board, and supported by the Office of the Surgeon General, Department of the Army, Washington, D. C.

² Present address: Communicable Disease Center, Virus and Rickettsia Section, P.O. Box 61, Montgomery, Alabama.