HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Stahmann, M. A. Articles by Matthews, R. E. F. Search for Related Content PubMed PubMed Citation Articles by Stahmann, M. A. Articles by Matthews, R. E. F.

The Effect of a Synthetic Lysine Polypeptide upon the Velocity of Precipitation of Tobacco Mosaic Virus by Its Antiserum¹

From the Departments of Biochemistry and Plant Pathology, University of Wisconsin, Madison, Wisconsin

Abstract

When small amounts of a basic synthetic lysine polypeptide preparation are added to tobacco mosaic virus along with its specific antiserum, both the antiserum and the polypeptide react simultaneously with the virus to cause an increase in the velocity of precipitate formation. However, when larger amounts are added to the virus before the antiserum, the polypeptide rapidly combines with the acidic surface of the virus and then at certain ratios of virus to polypeptide may interfere with subsequent combination with the antiserum and so decrease the velocity of precipitation. Precipitates are formed in the region of antigen excess in the presence of the polypeptide.

Footnotes

¹ Published with the approval of the Director of the Wisconsin Agricultural Experiment Station and supported in part by a grant from the Research Committee of the Graduate School from funds supplied by the Wisconsin Alumni Research Foundation.

² Present address: Plant Virus Research Unit, Molteno Institute, Cambridge, England.