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Infectivity Titrations of the Viruses of Western Equine Encephalomyelitis and Newcastle Disease by Tissue Culture Methods

From the Virus Laboratory, University of Otago Medical School, Dunedin, New Zealand

Abstract

The cytopathogenic changes which occur in tissue cultures infected with the viruses of Western equine encephalomyelitis or of Newcastle disease have been utilized for infectivity titrations of these agents.

The reproducibility and degree of accuracy exhibited by suspended tissue culture titrations compare favourably with those obtained by conventional animal inoculation methods.