HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Frank, H. G. Articles by Reiner, L. Search for Related Content PubMed PubMed Citation Articles by Frank, H. G. Articles by Reiner, L.

The Action of Fat-Acids on Trichomonas Vaginalis

From the Research Laboratories of Wallace and Tiernan Company, Belleville, New Jersey

Abstract

In studying the in vitro action of over 100 compounds on the motility of trichomonads, MacDonald and Tatum (1) observed that anionic, as well as cationic, surface-active agents are effective in immobilizing and disintegrating this organism. In view of the close chemical relationship between fat-acids and synthetic anionic surface-active agents, it seemed of interest to compare their activity on trichomonads. Trussell and Johnson (2) studied the trichomonacidal effects of various acids including a few fat-acids. Though these workers were conscious of the fact that variation of the hydrogen-ion concentration affects the viability of trichomonads and that it also may affect the action of acids on this organism, they made no efforts to control the pH value of their test-mixtures. Since the trichomonacidal concentrations of acids were determined by these workers at different pH values ranging from 4.1 to 6.3, comparison of the activity of fat-acids with each other and with that of surface-active agents at close to neutral pH value is impossible.