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The Hemagglutination Test for Rheumatoid Arthritis¹

II. The Influence of Human Plasma Fraction II (gamma Globulin) on the Reaction

From the Research, Medical and Out-Patient Services of the Veterans Administration Hospital, Bronx, N. Y.

Abstract

Two serological reactions have been described. The first reaction involves the inhibition of the hemagglutination test for rheumatoid arthritis by including human plasma Fraction II as a reagent. In the second reaction, the serum from individuals with active peripheral rheumatoid arthritis specifically agglutinated tannic acid-treated sheep erythrocytes sensitized with Fraction II. The heterogenic relationship of the reactants involved as well as the antigen-antibody-like character of these reactions are discussed.

Footnotes

¹ The work presented in this paper was aided in part by a grant from the New York Chapter of the Arthritis and Rheumatism Foundation, New York, N. Y.