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Studies in Specific Hypersensitiveness

II. A Comparison of Various Pollen Extracts with Reference to the Question of Their Therapeutic Value in Hay Fever

From the Department of Bacteriology and Immunology, Division of Immunology, Cornell University Medical College, and the First Medical Division of the New York Hospital

Abstract

The following study of the relative strengths of various commercial extracts used in the treatment of hay fever was made because there is no recognized standard method of preparation of such extracts and it was felt that it might be of interest to see what therapeutic results might reasonably be expected from their use. Preparations of four of the best known commercial products were purchased from a pharmacy and compared with corresponding extracts obtained from the Department of Applied Immunology in the New York Hospital. The method of preparation of these latter extracts is published by Dr. A. F. Coca in this issue of the Journal of Immunology (1). The commercial products have been designated A, B, C, and D, while those made in the New York Hospital are labelled E. For convenience the last named extracts will be referred to as the "Cornell preparations." All of the five preparations were in fluid form.