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Postnatal Immunity in Mouse Encephalomyelitis

From the Division of Laboratories and Research, New York State Department of Health, Albany

Abstract

Passive immunity to mouse encephalomyelitis virus is transmitted from immune female mice to their offspring both prenatally by placental transmission and postnatally by the mother's milk. The motheR's milk affords greater protection than placental transmission but resistance is greatest in baby mice acquiring immunity by both routes. The inhibiting agent in mouse milk is associated with the lactoglobulin fraction. The nature of the protective agent acquired by placental transmission is unknown.