HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Evans, A. S. Search for Related Content PubMed PubMed Citation Articles by Evans, A. S.

The Occurrence of Newcastle Disease Antihemagglutinin in Human Sera and Its Relationship to Mumps Virus¹

From the Section of Preventive Medicine, Yale University, School of Medicine, New Haven, Connecticut

Abstract

1. A serological and epidemiological survey of poultry workers exposed to Newcastle disease virus (NDV) thru infections in their chickens failed to reveal evidence that this agent had been responsible for human illness in this group.

2. An inhibitor of hemagglutination by NDV was found in sera from such exposed individuals and just as frequently in sera from individuals not similarly exposed. The occurrence of this inhibitor was found to be closely related to the occurrence of mumps antibodies. Cross absorption studies of such sera with NDV and mumps virus suggested that the NDV inhibitor represented an immunological overlap to infection by mumps virus. Similar interrelationships were not demonstrable in such sera by cross absorption experiments with influenza virus, nor in absorption experiments with specific antisera to NDV or mumps virus.

3. NDV may share antigenic components similar to or identical with antigenic components present in other infectious agents.

Footnotes

¹ Representing work done in part for the Commission of Virus and Rickettsial Diseases, Armed Forces Epidemiological Board, Office of the Surgeon General, Dept. of the Army, Washington, D. C.