HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hilleman, M. R. Articles by Helmold, R. J. Search for Related Content PubMed PubMed Citation Articles by Hilleman, M. R. Articles by Helmold, R. J.

The Indirect Complement Fixation, Hemagglutination and Conglutinating Complement Absorption Tests for Viruses of the Psittacosis-Lymphogranuloma Venereum Group¹

From the Department of Virus and Rickettsial Diseases, Army Medical Department Research and Graduate School, Washington, D. C.

Abstract

Three new tests for demonstrating antibody against viruses of the psittacosis-lymphogranuloma venereum group are described. These are the indirect complement fixation test, which detects inhibitory antibody for these viruses in the sera of chickens, the hemagglutination inhibition technique for testing human and chicken sera and the conglutinating complement absorption test for use with sera from patients. The possible application of the indirect complement fixation and agglutination inhibition tests to the study of infection with these viruses in avian populations is discussed. The relative merits and demerits of the three tests as compared with the ordinary complement fixation test are also reviewed.

Theoretical considerations regarding the mechanism of the indirect complement fixation test, the nature of the meningopneumonitis hemagglutinin and the inhibition of hemagglutination by calcium ion are discussed.

Footnotes

¹ Research Fellow, Commonwealth Fund.

This article has been cited by other articles:

				S. E. MOOLTEN and E. CLARK VIREMIA IN ACUTE HEMOLYTIC ANEMIA AND IN AUTOHEMAGGLUTINATION: Report of a Case and Review of the Literature, with Special Reference to the Virus of Newcastle Disease Arch Intern Med, February 1, 1952; 89(2): 270 - 292. [Abstract] [PDF]

				T. Kuwata Multiplication of Rickettsia tsutsugamushi and Ornithosis Virus in Transplantable Mouse Tumors Science, December 14, 1951; 114(2972): 640 - 641. [PDF]