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The Journal of Immunology, 1951, 66: 1-8.
Copyright © 1951 by The American Association of Immunologists, Inc.
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The Failure of Hyaluronidase to Influence Growth of PR8 Virus in Chick Embryos

Lyle B. Fastier

Microbiology Research Department of the New Zealand Medical Research Council, University of Otago Medical School, Dunedin, New Zealand

Abstract

A study has been made of the effect of two partially purified bacterial hyaluronidases (streptococcal and pneumococcal) and one commercial product of testicular origin (‘Alidase’) on growth of PR8 virus in the chick embryo. Evidence has been presented to show that these enzyme preparations failed to increase either the infectivity or the yield of this virus when inoculated within the allantoic cavity.






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