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Infection of Cynomolgus Monkeys with the Ohio Type of Coxsackie Virus (C Virus)¹

Section of Preventive Medicine, Yale University School of Medicine, New Haven, Connecticut

Abstract

Cynomolgus monkeys may be infected with the Ohio type of C virus; in contrast, rhesus and cercopithecus monkeys show no such susceptibility. This has been shown to be true with 3 different strains of the Ohio type, all immunologically related.

Evidences of infection in the monkey are: the development of fever and a virus carrier state both in the intestines and in the throat. Additional evidence for infection is the formation of neutralizing and complement fixing antibodies.

Footnotes

¹ Aided by a grant from the National Foundation for Infantile Paralysis, Inc.

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