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The Journal of Immunology, 1949, 61: 297-306.
Copyright © 1949 by The American Association of Immunologists, Inc.
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The Application of a Quantitative Complement-Fixation Method to a Study of Q Fever Strain Differentiation

Don M. Wolfe and Lottie Kornfeld

From the Section of Viral and Rickettsial Research, Lederle Laboratories Division, American Cyanamid Company, Pearl River, N. Y.

Abstract

1. A quantitative complement-fixation method has been applied to the rickettsial antigens of Q fever.
2. Significant differences in the titers of antigens prepared as outlined from two strains of Q fever were not detected under the conditions of the present test.
3. Human Q fever serums of European and American origin, when tested with Nine Mile and Henzerling antigens, gave similar titers in both instances.






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