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The Antibody Response of Rabbits to a Single Injection of Type I Pneumococci^*

(From the Department of Microbiology, New York University College of Medicine; the Department of Medicine, College of Physicians and Surgeons, Columbia University, the Presbyterian Hospital in the City of New York, and the Bureau of Laboratories of the Department of Health of the City of New York)

Abstract

1. The sera of rabbits subjected to a single antigenic stimulus with Type I pneumococci were analyzed for antibodies to the commonly recognized pneumococcal antigens.

2. The data are tabulated and are found comparable to similar analyses of sera of human patients recovered from pneumococcal infections and of human subjects injected with small quantities of pneumococci or type-specific pneumococcal polysaccharides.

Footnotes

^* The work reported in this communication was carried out in part under the Commission on Acute Respiratory Diseases, Army Epidemiological Board, Office of the Surgeon General, United States Army, and in part under the Harkness Research Fund of the Presbyterian Hospital, New York.