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The Effect of Adrenocorticotrophic Hormone and X-Ray on the Amount of Circulating Antibody^*

Edward E. Fischel, Marjorie LeMay and Elvin A. Kabat

From the Departments of Medicine, Radiology, Neurology and Bacteriology, College of Physicians and Surgeons, Columbia University, The Presbyterian Hospital and The Neurological Institute, New York

Abstract

An anamnestic rise in circulating antibody following administration of adrenocorticotrophic hormone or of X-ray could not be demonstrated by the quantitative precipitin-method in rabbits three months after cessation of immunization with crystalline ovalbumin despite the occurrence of a concomitant decrease in circulating lymphocytes.

Footnotes

^* Aided in part by grants from the William J. Matheson Commission and the Edward Daniels Faulkner Arthritis Clinic.

This work was done during the tenure of a Life Insurance Medical Research Fellowship.